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Mechanism Explainers

How peptide classes work at the molecular level — signal pathways, receptor pharmacology, and pharmacokinetic distinctions.

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Metabolic
GLP-1 Receptor Agonism

How incretin mimetics regulate glucose metabolism, appetite, and gastric emptying through GLP-1R activation.

Insulin secretion Appetite regulation GLP-1R
Updated Jul 2026
Metabolic
GIP / GLP-1 Dual Agonism

How dual incretin agonists like tirzepatide achieve additive metabolic effects through combined GIP and GLP-1 receptor activation.

Tirzepatide Dual agonism Weight loss
Updated Aug 2026
Growth hormone
GHRH / GHRP Axis

Growth hormone releasing pathways — how secretagogues, GHRH analogs, and ghrelin mimetics interact with the somatotropic axis.

Somatotropic axis Secretagogues IGF-1
Updated Aug 2026
Immune
Thymic Peptide Signaling

How thymosin and thymulin class peptides modulate T-cell maturation and immune regulation through thymic pathways.

T-cell maturation Thymosin alpha-1 Immune modulation
Updated Jun 2026
Neuroprotective
Melanocortin Receptors

MC1R–MC5R receptor subtypes, their peptide ligands, and roles in inflammation, appetite, and sexual function.

MC receptor subtypes PT-141 α-MSH
Updated Jul 2026
Tissue repair
Angiogenic Peptide Pathways

VEGF, FGF, and EGF signaling in tissue repair — how peptides like BPC-157 and TB-500 interact with growth factor cascades.

VEGF FGF Wound healing
Updated Jul 2026
Growth hormone
IGF-1 Signaling Cascade

How insulin-like growth factor 1 mediates downstream effects of growth hormone on tissue growth, repair, and metabolic regulation.

IGF-1R Somatomedin Cell proliferation
Updated Aug 2026
Immune
BPC-157 Multi-Pathway Model

Why BPC-157 resists clean mechanistic classification — NO system, dopaminergic interaction, and growth factor upregulation as parallel pathways.

Nitric oxide Dopamine Cytoprotection
Updated Aug 2026
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